[Biological markers of myocardial necrosis].

Author’s response to reviews Title: Abnormal elevation of myocardial necrosis biomarkers after coronary artery bypass grafting without established myocardial infarction assessed by cardiac magnetic resonance Authors:

Myocardial Infarction in a Rhesus Monkey

Myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. The outcome of myocardial necrosis varies depending on the extent of the damage (Donald 2001, Jubb 1993, Radostits 1994, Vanvaleet 1986). Myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (Gonder 1...

New Biomarkers of Ischemia

The traditional biomarkers, CK-MB and troponins, used for the diagnosis of myocardial ischemia and the risk stratification of patients with acute coronary syndromes (ACS) are of limited use mainly because they require some degree of necrosis in order to become detectable. Based on the knowledge gained into the pathophysiology of ACS, several new biomarkers have been developed. Brain natriuretic...

Biomarkers in Acute Myocardial Infarction

Acute coronary syndrome (ACS) is a significant cause of morbidity and mortality worldwide. Patients can be stratified by symptoms, risk factors and electrocardiogram results but cardiac biomarkers also have a prime role both diagnostically and prognostically. The proper diagnosis of ACS requires reliable and accurate biomarker assays to detect evidence of myocardial necrosis. Currently, troponi...

CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: clinical use of inflammatory markers in patients with cardiovascular diseases: a background paper.

Inflammation is a recognized key component of acute coronary syndromes. Such pathogenetic achievement has led to the use of inflammatory cells and proteins as prognostic markers in these syndromes. A number of markers have been proposed, including proinflammatory cytokines such as interleukin-6, interleukin-1RA, and tumor necrosis factor-alpha, adhesion molecules such as intracellular adhesion ...